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High Level of Hygiene Associated With Wheeze And Eczema Risk in Infants NEW YORK (Reuters Health) Jul 31 - An environment with a high level of hygiene may increase the risk of wheeze and atopic eczema in young children, according to a report in the July issue of the Archives of Disease in Childhood. Dr. Andrea Sherriff from the University of Bristol, UK, and colleagues collected data for 10,970 children who participated in the Avon Longitudinal Study of Parents and Children. Parents completed questionnaires about their children´s symptoms of wheeze and eczema when the children were between 0 and 6 months old and again when they were between 30 and 42 months old. The parents also completed a hygiene score questionnaire, which ranked the level of hygiene in the home from least hygienic to most hygienic. As hygiene scores increased, so did the wheeze and atopic eczema levels in the children between 30 and 42 months, Dr. Sherriff´s team found. However, neither wheeze nor atopic eczema increased with higher hygiene scores during the first 6 months, the researchers note. "We have established an independent association between infant hygiene score and both wheeze and atopic eczema reported during the period 30 to 42 months, which supports the hygiene hypothesis," Dr. Sherriff´s group concludes. While "the importance of hygiene in public health should not be dismissed;" they add, "the creation of a sterile environment through excessive cleanliness may potentially be harmful to the immune system." Arch Dis Child 2002;87:26-29.
High Level of Hygiene Associated With Wheeze And Eczema Risk in Infants NEW YORK (Reuters Health) Jul 31 - An environment with a high level of hygiene may increase the risk of wheeze and atopic eczema in young children, according to a report in the July issue of the Archives of Disease in Childhood. Dr. Andrea Sherriff from the University of Bristol, UK, and colleagues collected data for 10,970 children who participated in the Avon Longitudinal Study of Parents and Children. Parents completed questionnaires about their children´s symptoms of wheeze and eczema when the children were between 0 and 6 months old and again when they were between 30 and 42 months old. The parents also completed a hygiene score questionnaire, which ranked the level of hygiene in the home from least hygienic to most hygienic. As hygiene scores increased, so did the wheeze and atopic eczema levels in the children between 30 and 42 months, Dr. Sherriff´s team found. However, neither wheeze nor atopic eczema increased with higher hygiene scores during the first 6 months, the researchers note. "We have established an independent association between infant hygiene score and both wheeze and atopic eczema reported during the period 30 to 42 months, which supports the hygiene hypothesis," Dr. Sherriff´s group concludes. While "the importance of hygiene in public health should not be dismissed;" they add, "the creation of a sterile environment through excessive cleanliness may potentially be harmful to the immune system." Arch Dis Child 2002;87:26-29.