תסמונת מרפן
שלום רב! תסמונת מרפו פוגעת בעין על ידי גרימת נקיעה של העדשות,קוצר ראיה גבוה,סיכון יתר להתפתחות היפרדות רשתית,פזילה. אני מצרף חומר על הנושא באנגלית ( ניתן לחפש באינטרנט Marfan ויש אתרים רבים): Reduced vision - About 65 % of Marfan’s patients develop ectopia lentis. This is a dislocation of the lens of the eye, which is caused by a weakness in tiny eye ligaments that normally hold the lens in place. Marfan’s syndrome also seems to increase the risk for myopia (nearsightedness); cataracts at an unusually early age (age 40to 50); glaucoma, retinal detachment and strabismus. Subluxation of the lens is the most common ocular abnormality, which is bilateral and symetrical. The dislocation may be complete, with the lens floating free within the vitreous cavity. Iridodonesis (tremulousness of the iris) may occur from nonsupport of the overlying iris by the lens. The axial length of the globe is increased in Marfan´s patients leading to moderate to severe myopia as the most common refractive error. Retinal detachment is more common than in the normal population. Glaucoma may be the result of the angle anomaly or it may be associated with lens subluxation. Children with Marfan´s syndrome require regular ophtalmologic surveillance to correct visual acuity and thus prevent amblyopia. Patients of all ages require echocardiography annualy to monitor aortic diameter and mitral valve function, and should use standard endocarditis prophylaxis.
