מחקר ישראלי מ2006 מעלה אצלי שאלות. מור?
קראתי מחקר ישראלי משנת 2006 שמתאר את הסיבות מדוע הפסיקו ב2005 לחסן את ילדי ישראל עם (החיסון המת) IPV + (החיסון החי) OPV ומאז רק עם IPV
The most important reasons for omitting OPV from the vaccination program are discussed below:
• Recent studies in Israel demonstrated that contrary to former belief, OPV when administered together with IPV,
may not confer significant “gut immunity” against infection by polio virus (T. Swartz, personal communication, 2004).
According to the results of recent studies, the addition of OPV to IPV does not confer a significant benefit over the
IPV only program, but it does have definitive risks (see below).
• In the last 3–5 years, outbreaks of circulating vaccineb associated paralytic polio have been reported in Haiti, the
Dominican Republic and Madagascar, and have since been recognized as responsible for outbreaks that occurred in
Egypt in the 1960s [5].
• Revertant OPV type 2 with mutations developing over time and differing from the vaccine strain by 9–14.2% have been
repeatedly isolated from the sewage of the Tel Aviv area since 1998. These revertant vaccinebderived viruses have
been shown to be invasive and neurovirulent in mice [6, and L. Shulman, personal communication, 2004].
• The WHO has decided to implement simultaneous global cessation of OPV vaccination soon after global polio eradib
cation in order to prevent vaccinebassociated outbreaks [7]. OPV is not safe in a world where vaccination coverage is
not high and where the number of immunocompromised patients continues to increase as a result of cancer treatment, organ transplantations
and AIDS.
When weighing the unproven benefits of adding OPV to the IPV program with the definitive and proven risk of OPV, the Israel
Ministry of Health has decided to discontinue administration of OPV.
http://www.ima.org.il/FilesUpload/IMAJ/0/48/24101.pdf
לאור הנ"ל במיוחד סעיפים 1 ו-3 - מדוע משרד הבריאות מתעקש לחסן עם OPV ? ומדוע הוא טוען שיש "אפס" סיכוי לחלות למי שמחוסן לאור הנ"ל ?
קראתי מחקר ישראלי משנת 2006 שמתאר את הסיבות מדוע הפסיקו ב2005 לחסן את ילדי ישראל עם (החיסון המת) IPV + (החיסון החי) OPV ומאז רק עם IPV
The most important reasons for omitting OPV from the vaccination program are discussed below:
• Recent studies in Israel demonstrated that contrary to former belief, OPV when administered together with IPV,
may not confer significant “gut immunity” against infection by polio virus (T. Swartz, personal communication, 2004).
According to the results of recent studies, the addition of OPV to IPV does not confer a significant benefit over the
IPV only program, but it does have definitive risks (see below).
• In the last 3–5 years, outbreaks of circulating vaccineb associated paralytic polio have been reported in Haiti, the
Dominican Republic and Madagascar, and have since been recognized as responsible for outbreaks that occurred in
Egypt in the 1960s [5].
• Revertant OPV type 2 with mutations developing over time and differing from the vaccine strain by 9–14.2% have been
repeatedly isolated from the sewage of the Tel Aviv area since 1998. These revertant vaccinebderived viruses have
been shown to be invasive and neurovirulent in mice [6, and L. Shulman, personal communication, 2004].
• The WHO has decided to implement simultaneous global cessation of OPV vaccination soon after global polio eradib
cation in order to prevent vaccinebassociated outbreaks [7]. OPV is not safe in a world where vaccination coverage is
not high and where the number of immunocompromised patients continues to increase as a result of cancer treatment, organ transplantations
and AIDS.
When weighing the unproven benefits of adding OPV to the IPV program with the definitive and proven risk of OPV, the Israel
Ministry of Health has decided to discontinue administration of OPV.
http://www.ima.org.il/FilesUpload/IMAJ/0/48/24101.pdf
לאור הנ"ל במיוחד סעיפים 1 ו-3 - מדוע משרד הבריאות מתעקש לחסן עם OPV ? ומדוע הוא טוען שיש "אפס" סיכוי לחלות למי שמחוסן לאור הנ"ל ?